Hormones are the signaling molecules that regulate the physiology of the body. These are also known as chemical messengers. Hormones are secreted from the endocrine glands. Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders. It is characterized by impaired cortisol synthesis in the cortex of the adrenal gland.
- SIGNS AND SYMPTOMS OF CONGENITAL ADRENAL HYPERPLASIA
- CAUSES OF CONGENITAL ADRENAL HYPERPLASIA
- PATHOPHYSIOLOGY OF CONGENITAL ADRENAL HYPERPLASIA
- DIAGNOSIS OF CONGENITAL ADRENAL HYPERPLASIA
- TREATMENTS FOR CONGENITAL ADRENAL HYPERPLASIA
- PROGNOSIS OF CONGENITAL ADRENAL HYPERPLASIA
- COMPLICATIONS OF CONGENITAL ADRENAL HYPERPLASIA
- CONGENITAL ADRENAL HYPERPLASIA AND AYURVEDA
- NIDANA- AYURVEDIC CAUSES OF CONGENITAL ADRENAL HYPERPLASIA
- PURVAROOPAM- AYURVEDIC PREMONITORY SYMPTOMS OF CONGENITAL ADRENAL HYPERPLASIA
- SAMPRAPTI – AYURVEDIC PATHOGENESIS OF CONGENITAL ADRENAL HYPERPLASIA
- LAKSHANA- AYURVEDIC SIGNS AND SYMPTOMS OF CONGENITAL ADRENAL HYPERPLASIA
- AYURVEDIC PROGNOSIS OF CONGENITAL ADRENAL HYPERPLASIA
- CHIKITSA- AYURVEDIC TREATMENT FOR CONGENITAL ADRENAL HYPERPLASIA
- AYURVEDIC SAMANA TREATMENT FOR CONGENITAL ADRENAL HYPERPLASIA
- AYURVEDIC SHODHANA TREATMENT FOR CONGENITAL ADRENAL HYPERPLASIA
- COMMONLY USED AYURVEDIC MEDICINES FOR CONGENITAL ADRENAL HYPERPLASIA
- HOME REMEDIES FOR CONGENITAL ADRENAL HYPERPLASIA
- DIET AND BEHAVIOUR FOR CONGENITAL ADRENAL HYPERPLASIA
- YOGA FOR CONGENITAL ADRENAL HYPERPLASIA
- RESEARCH PAPERS OF AYURVEDIC MANAGEMENT OF CONGENITAL ADRENAL HYPERPLASIA
SIGNS AND SYMPTOMS OF CONGENITAL ADRENAL HYPERPLASIA
- Vomiting
- Dehydration
- Ambiguous genitalia
- Precocious puberty
- Early pubic hair
- Excessive facial hair
- Anovulation
- Enlarged clitoris and shallow vagina
- Severe acne
CAUSES OF CONGENITAL ADRENAL HYPERPLASIA
- Adrenal hyperplasia is an inherited condition caused by a gene mutation
- Mutation occurs in the genes that codes for enzymes involved in the formation of steroid hormones from the adrenal gland.
PATHOPHYSIOLOGY OF CONGENITAL ADRENAL HYPERPLASIA
Due to the above-mentioned cause, the adrenal gland produces excess amounts of male hormones leading to the symptoms of congenital adrenal hyperplasia. The 21 hydroxylase enzyme deficiency is the most common type of congenital adrenal hyperplasia.
DIAGNOSIS OF CONGENITAL ADRENAL HYPERPLASIA
- Diagnosis through clinical features
- Blood tests – to measure the level of hormones
- Prenatal testing like amniocentesis and chorionic villus sampling
- Genetic testing
TREATMENTS FOR CONGENITAL ADRENAL HYPERPLASIA
- Hormone replacement for hormone deficiency
- Surgical interventions
PROGNOSIS OF CONGENITAL ADRENAL HYPERPLASIA
- Symptoms of congenital adrenal hyperplasia are manageable with lifelong medications and surgical treatments. If it is untreated leads to complications.
COMPLICATIONS OF CONGENITAL ADRENAL HYPERPLASIA
- Hyponatremia (low blood sodium levels)
- Cardiovascular diseases
CONGENITAL ADRENAL HYPERPLASIA AND AYURVEDA
- In Ayurveda congenital adrenal hyperplasia is managed based on the symptoms.
NIDANA- AYURVEDIC CAUSES OF CONGENITAL ADRENAL HYPERPLASIA
- Janma krita – congenital
Risk of developing CAH is the practice of below-mentioned factors by the pregnant lady;
- Excess consumption of ununctuous, cold, incompatible food
- Suppression of natural urges.
- Hyper or hypo functioning of agni
- Rathri jagarana – awakening at night
PURVAROOPAM- AYURVEDIC PREMONITORY SYMPTOMS OF CONGENITAL ADRENAL HYPERPLASIA
- No premonitory symptoms
SAMPRAPTI – AYURVEDIC PATHOGENESIS OF CONGENITAL ADRENAL HYPERPLASIA
Hyper or hypo functioning of dhatu agni leads to symptoms of congenital adrenal hyperplasia. The Adrenal gland and Kidney (Vrikka) together form the Moolasthana (origin or governing site) for Medovaha Srotas (channels carrying nutrition). Medas (adipose tissue) being Pruthvi (earth elements) and Jala (water elements) predominant area, Kapha dosha will be dominant in this area. There will be the involvement of Apana Vata (type of vata) also in this area. The Lakshana or symptoms of patients often shows the possibility that there is Vata Prakopa (vitiation of Vata) and Kapha Kshaya (decreased kapha) in the stage of foetal development.
LAKSHANA- AYURVEDIC SIGNS AND SYMPTOMS OF CONGENITAL ADRENAL HYPERPLASIA
- Chardi – vomiting
- Pourusha bahulyatha in female
- Vandhyatwam – infertility in females due to anovulation
AYURVEDIC PROGNOSIS OF CONGENITAL ADRENAL HYPERPLASIA
- Yapya roga – symptoms are manageable with Ayurvedic medicines
CHIKITSA- AYURVEDIC TREATMENT FOR CONGENITAL ADRENAL HYPERPLASIA
AYURVEDIC SAMANA TREATMENT FOR CONGENITAL ADRENAL HYPERPLASIA
- Kanchanara guggulu – for glandular diseases (grandhi roga)
- Aswagandha churna
- Treatment for deranged agni
AYURVEDIC SHODHANA TREATMENT FOR CONGENITAL ADRENAL HYPERPLASIA
- NASYA-Ksheerabala
COMMONLY USED AYURVEDIC MEDICINES FOR CONGENITAL ADRENAL HYPERPLASIA
Internal administration for grandhi roga are used to treat congenital adrenal hyperplasia
- Kanchanara guggulu
- Swayamagni bhasma
- Drakshadi kashaya
- Sarivasava
- Vyoshadi guggulu
- Guduchyadi kashaya
HOME REMEDIES FOR CONGENITAL ADRENAL HYPERPLASIA
- Exercise regularly
- Take an appropriate quantity of fluids
DIET AND BEHAVIOUR FOR CONGENITAL ADRENAL HYPERPLASIA
- Avoid food items that produce dosha imbalance like cold and dry food, hard to digest. Because dosha imbalance aggravates the symptoms.
- Avoid more oily foods, junk foods
- Consume a balanced diet
YOGA FOR CONGENITAL ADRENAL HYPERPLASIA
- Nadi Shuddi Pranayam
The patient needs to be seated in a meditative posture with the head and spine erect, with the body relaxed. The patient has to close his one nostril (e.g. left nostril if using the right hand and vice versa) with the thumb and exhale completely through the other nostril. Again, he will have to breathe in deeply through the other nostril while the opposite nostril is still closed with the thumb.
- Savasana – relaxes the body and mind
RESEARCH PAPERS OF AYURVEDIC MANAGEMENT OF CONGENITAL ADRENAL HYPERPLASIA
- Ashwagandha root in the treatment of non-classical adrenal hyperplasia
https://pubmed.ncbi.nlm.nih.gov/22987912/
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